China (Mainland)
Peptides Tb500 Thymosin Beta-4 for Repairing Tissue in Joints CAS NO.77591-33-4
- FOB Price: USD: 6.00-6.00 /Metric Ton Get Latest Price
- Min.Order: 1 Metric Ton
- Payment Terms: L/C,D/A,D/P,T/T,
- Available Specifications:
GMP(1-9)Metric Ton
- Product Details
Keywords
- tb-500
- 77591-33-4
- gh
Quick Details
- ProName: Peptides Tb500 Thymosin Beta-4 for Rep...
- CasNo: 77591-33-4
- Molecular Formula: C212H350N56O78S?
- Appearance: white powder
- Application: Recent laboratory research and clinica...
- PackAge: Plastic Vial(Dedicated for Peptide Pac...
- Port: ShangHai
- ProductionCapacity: 1000 Kilogram/Month
- Purity: 99%
- Storage: Dry Cool Place
- LimitNum: 1 Metric Ton
Superiority
Why us
| 1. 1 Quality assurance | With our years of experience, advanced technology and continuous research, our quality is to fully meet the needs of the market to meet the requirements of customers, many customers use our products, we believe that the product is very good. |
| 1. 2. Safe transportation | Our mode of transport is taken according to each country's situation is different transportation, while our packaging, according to the latest customs situation, constantly updated, improved our packaging, we guarantee that you receive it within 3-7 working days. |
| 1. 3. High quality service : | Best Service with after-sales service and consultation,we have an excellent customer service driven approach to our business, unlike most sites we are consistently available via Facebook, email, skype or whatsapp and always respond quickly. |
| 1. 4. Reship policy | yes, dear, in case failed to ge |
We are the direct factory which is located in zhengzhou, Henan province. We also specialize in the research, development and production of kinds of Amino Acids,Pharmaceutical Polypeptide,Comestic Polypeptide,Vetenary Peptide and Pharmaceutical APIs. We provide good quality and best price with professinal technique.
1.COA HPLC MS be sent on request
2.A-Grade
3.competitive price
4.Fast delivery
1)Delivery: Immediately by DHL/EMS/TNT within 10 days (If you have Forwarder in China,
the better.)
2) Payment Terms: Bank Transfer,MoneyGram and western union.
Please feel free to contact us if you have any other requirement, we accept custom-made.Most competitive price, best quality and best service will be provided.
Details
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TB-500 (Thymosin B4) |
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|
Quantity: |
2mg |
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Purity: |
>99% by HPLC |
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CAS NO.: |
77591-33-4 |
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Molecular Formula: |
C212H350N56O78S |
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Molecular Weight: |
4963.4408 |
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Appearance: |
Sterile filtered white lyophilized (freeze-dried) powder |
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AA Sequence: |
Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser |
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Reconstitution: |
We recommend that this vial be briefly centrifuged prior to opening to settle the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20°C. Further dilutions should be made in appropriate buffered solutions. |
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Storage: |
This lyophilized preparation is stable at room temperature when garded from light, but should be kept at -20°C for long term storage, preferably with dessicant. Upon reconstitution, the preparation is stable when stored at 2-8°C. For maximum stability, apportion the reconstituted preparation into working aliquots and store at -20°C. Avoid repeat freeze/thaw cycles. |
TB-500 (Thymosin Beta-4)
TB-500 is a synthetic version of the naturally occurring peptide present in virtually all human and animal cells, Thymosin Beta-4. This potent peptide is a member of a ubiquitous family of 16 related molecules with a high conservation of sequence and localization in most tissues and circulating cells in the body. TB-500 not only binds to actin, but also blocks actin polymerization and is the actin-sequestering molecule in eukaryotic cells.
TB-500 was identified as a gene that was up-regulated four-to-six fold during early blood vessel formation and found to promote the growth of new blood cells from the existing vessels. This peptide is present in wound fluid and when administered subcutaneously, it promotes wound healing, muscle building and speeds up recovery time of muscles fibres and their cells. An additional key factor of TB-500 is that it promotes cell migration through a specific interaction with actin in the cell cytoskeleton. It has been demonstrated that a central small amino acid long-actin binding domain has both blood cell reproduction and wound healing characteristics. These characteristics are uncovered by accelerating the migration of endothelial cells and keratinocytes. It also increases the production of extracellular matrix-degrading enzymes.
Studies demonstrate that TB-500 is a potent, naturally occurring wound repair factor with anti-inflammatory properties. Tß4 is different from other repair factors, such as growth factors, in that it promotes endothelial and keratinocyte migration. It also does not bind to the extracellular matrix and has a very low molecular weight meaning it can travel relatively long distances through tissues. One of TB-500 key mechanisms of action is its ability to regulate the cell-building protein, Actin, a vital component of cell structure and movement. Of the thousands of proteins present in cells, actin represents up to 10% of the total proteins which therefore plays a major role in the genetic makeup of the cell.