Terlipressin Acetate??by lab CAS NO.14636-12-5

Filter  is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates in China.

2. The yearly production capacity is 50000MT, 80% for export.We have a professinal export team. Both by Air and by Sea,we ensure that we meet the customer expectations with promptness.
3. Our company facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service.
4. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.

terlipressin Acetate
CAS No.: 14636-12-5
EINECS: 238-680-8
Molecular Formula: C52H74N16O15S2
Molecular Weight: 1227.37
Appearance: White powder
Grade: Pharmaceutical Grade
Usage: Norepinephrine-resistant septic shock, bleeding esophageal varices, and for the complications of cirrhosis of the liver (esophageal and gastric variceal bleeding, ascites, liver and kidney syndrome) has important significance for the treatment of patients.

Description: 

Terlipressin (trade names Teripress by New Medicon Pharma and Glypressin by Ferring Pharmaceuticals) is an analogue of vasopressin used as a vasoactive drug in the management of hypotension. It has been found to be effective when norepinephrine does not help.
Indications for use include norepinephrine-resistant septic shock and hepatorenal syndrome. In addition, it is used to treat bleeding esophageal varices.
Between the patients with cirrhosis of the liver into the portal circulation of each vein and venous congestion can occur in vascular anastomosis, portal vein pressure rise phenomenon. The most frequently appeared in the azygos vein anastomosis with lower esophageal varices, instant tube.

Application:
This product is pressurized prodrug hormone, vasopressin glycyl in into the blood after enzymatic hydrolysis in the molecule is produced a continuous low level. The portal venous pressure it generates the desired effect, but the changes of arterial blood pressure than the use of vasopressin after much smaller, and the blood of a few do not increase the fibrinolytic. Push once its role can be maintained for about 4 ~ 6h.