Recombinant Human Epidermal Growth Factor CAS NO.616204-22-9
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- Min.Order: 100 Milligram
- Payment Terms: L/C,D/A,D/P,T/T,
- Available Specifications:
Pharmaceutical (0-100)Milligram
- Product Details
Keywords
- rh-EGF
- EGF
- Epidermal Growth Factor
Quick Details
- ProName: Recombinant Human Epidermal Growth Fac...
- CasNo: 616204-22-9
- Molecular Formula: C34H60N14O12S
- Appearance: White Crystal Powder
- Application: Epidermal growth factor, also known as...
- DeliveryTime: 24 hours
- PackAge: According to Customer's Requirement
- Port: Shanghai
- ProductionCapacity: 100 Gram/Day
- Purity: 99%
- Storage: Keep Cold
- Transportation: Shipment : TNT ,DHL ,HKEMS ,HKEUB ,FED...
- LimitNum: 100 Milligram
- Related Substances: Recombinant Human Epidermal Growth Fac...
- Residue on Ignition: 0
- Heavy Metal: 0
- Valid Period: 2 years
- Storage: Store the shade
- Function: Skin Care
Superiority
Quality
Our company is a professional production of hormone intermediates for many years, our products have exported to Germany,Spain, UK, USA, Australia, Middle East, and so on other country, and we have got very good feedback from our customers, you can trust us.And we are the manufactory, so no problem for us to control the quality.
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Western Union,TT,Money Gram
Service
Best service with after-sales service to all clients.
Delivery
Sample Order :Package will be shipped with 3days after payment. We can send it via UP, EMS, HK Air Post, DHL or othermethod. We have a professional and stable logistics, and we can deliver the package smoothly around 3 to 5 days.
Details
Introduction of recombinant human epidermal growth factor
1.Epidermal growth factor, also known as oligopeptide-1, is an active substance in the human body and consists of an active polypeptide consisting of 53 amino acids. By stimulating the tyrosine phosphorylation of epidermal growth factor receptor, it can repair hyperplastic skin. Epidermal cells, which directly promote epidermal growth, are designated as epidermal growth factor (EGF) for this purpose.
A brief introduction of human epidermal growth factor
No EEGF glycosylation site, very stable, heat acid, widely exists in various body fluids and glands, mainly composed of submandibular gland, duodenum, have been found in the body of the vast majority of body fluids, specific content increased in milk, urine, semen, but the concentration in serum is low. Many experimental studies have shown that EGF stimulates the proliferation of many cells, mainly epidermal cells and endothelial cells. For the repair and healing of corneal injury, burns and surgery, it has achieved good results. Professor Montalcini and Cohen won the prize in physiology and medicine in 1986 because of the discovery of epidermal growth factor and analysis of its structure and function mechanism.
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Recombinant human epidermal growth factor application field
Clinical aspects
The role of the skeletal system
It promotes the formation of a large number of osteoblasts and inhibits osteoclasts. Treatment of osteoporosis, necrosis of the femoral head, arthritis, rheumatism, and disease caused by calcium deficiency. The role of the digestive system
Strengthen the gastrointestinal function, promote the digestion of digestive enzymes, improve appetite, and treat chronic gastritis.
The role of the blood system
To strengthen the hematopoietic function of bone marrow, promote the generation of stem cells, and then produce a large number of red cells and white blood cells. To strengthen the thickness of the left ventricle, enhance the elastic force of the myocardium, and to treat the heart disease efficiently. Effective scavenging of blood Medium and low density protein, prevent the deposition of blood vessel wall, treatment of thrombus.
The role of the respiratory system
Strengthen lung cell function, correction, cool blood barrier lung toxins, treatment of emphysema and pulmonary hypoxia and respiratory diseases. The role of the urinary system To promote the growth of human hormones, strengthen the secretion of various enzymes and hormones, strengthen the function of the kidney, strengthen the metabolism of water, and help the body to detoxify.
The role of the reproductive system
Stimulates sex hormone secretion, strong organ muscle tissue, strengthens the sexual organ nerve endurance, opens the microcirculation, speeds up the sexual organ congestive.
The role of the immune system
Stimulating thymus regeneration, accelerating the generation of lymphoid T cells, B cells, phagocytes, improving immune function, phagocytosis of viral pathogens and cancer cells, and treatment of cancer and cancer.
The function of the nervous system
We should speed up the recovery of nervous system function, promote the generation of brain neurons and dendrites, reverse brain atrophy, accelerate deep sleep, treat Alzheimer's disease, neurasthenia, memory loss, neuropathic headache and so on.
Cosmetology
Skin rejuvenation
Epidermal growth factor can stimulate the ectoderm and endoderm origin of various cells such as corneal epithelial and endothelial cells, epidermal and dermal cells (such as fibroblasts), mammary gland cells and stromal cells, the proliferation and migration, accelerate the The new supersedes the old. achieve the rejuvenation effect.
Moisturize the skin EGF
can promote the biosynthesis of DNA, RNA and functional proteins, and promote the synthesis of extracellular large molecules, such as hyaluronic acid, elastic fibrin and so on. It can increase skin moisture and increase skin elasticity and moisturize skin
Repair wounds
By binding to EGF receptors, stimulated epidermal cells (including epithelial cells from a variety of tissues, and various mesenchymal cells) enter the cell division cycle, and initiate activation, expression, and secretion of biologically active proteins in the cells. Promote the linear arrangement of collagen fibers, epidermal cells grow quickly and regularly and cover the wound in time. It significantly accelerates wound healing after cosmetic, cosmetic and other skin wounds, and keeps the wound flat and smooth, reducing or eliminating scars and reducing pigmentation
Prevent stains
Epidermal growth factor has a strong promotion effect on the proliferation of epidermal cells. After use, the epidermal cells become younger, so that there is less accumulation of pigment and dead cells in the epidermis, so that the skin appears white, flawless, and eliminates color. Abnormal skin manifestations such as spots and pigmentation. The use of EGF during the treatment and recovery of freckle can effectively curb the recurrence of pigmentation.
Eliminates wrinkles
Epidermal growth factor promotes the active transport of cellular nutrients from the outside of the cell to the cells, increasing intracellular nutrition. Promote the secretion of synthetic collagen fibers, polysaccharides, glycoproteins and other functional molecules in the dermis cells, so that the subcutaneous dermal tissue is full and the muscle fibers are arranged neatly and closely, thereby reducing and eliminating wrinkles.
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Animal cell culture
At present, the global demand for serum-free medium for animal cell culture is more in-depth, and the demand for various growth factors is very large. According to incomplete statistics, the annual demand for CHO serum-free medium alone is 600 tons
Comapny Profile
Filter Biotech Co., Ltd. is a high-tech company specializing in R&D, production and sales of APIs and preparations. It is committed to providing high-quality biological products to the world. Our company mainly promotes products to the world as r-hGH (recombinant human growth. Hormone), LR3-IGF-1 (long-acting recombinant human insulin-like growth factor 1 analogue), has established cooperative relations with customers in Russia, Israel, the United States, South Korea and other countries. Our company has always been adhering to the "Intention to serve, create The "value" concept focuses on the cause of human health, leads the future through innovation, and is guided by the needs of customers to continuously improve service quality.
Company Advantage
Expression system
1.The recombinant human epidermal growth factor (rhEGF) engineered strain produced by the company is a Pichia strain transformed with a recombinant plasmid containing a synthetic human epidermal growth factor gene.
2.Compared with Pichia pastoris,
Pichia pastoris is a unicellular eukaryote, which has the characteristics of rapid growth of prokaryotes, simple genetic manipulation, and a relatively complete post-translation processing modification function, which can effectively overcome the large intestine. Deficiency of Bacillus (E. coli does not have eukaryotic gene expression regulation mechanisms and protein processing capabilities, and the expressed protein is an inactive inclusion body).
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